Abstract #0466
Radial R2* distribution : a new method to analyze BOLD MRI of kidneys
Bastien Milani 1,2 , Maciej Piskunowicz 1,3 , Isabelle Bassi 1 , Christiane Anex 1 , Bruno Vogt 1,4 , Matthias Stuber 2,5 , Michel Burnier 1 , and Menno Pruijm 1
1
Department of Nephrology and Hypertension,
CHUV, Lausanne, Switzerland,
2
Center
for Biomedical Imaging (CIBM), Lausanne, Switzerland,
3
Department
of Radiology, Medical University of Gdansk, Gdansk,
Poland,
4
Department
of Nephrology and Hypertension, Bern University
Hospital, Bern, Switzerland,
5
Department of
Radiology, University Hospital (CHUV) and University of
Lausanne (UNIL), Lausanne, Switzerland
Blood oxygenation level dependent MRI (BOLD MRI) is a
mapping of R2* which is inversely correlated to the
concentration of blood haemoglobin. This abstract
presents two items: a new method for the post-processing
of renal BOLD MRI and an analysis of a clinical study on
the response of the R2* map to the diuretic furosemide
using our new post-processing method. This method is
based on the radial R2* distribution, which accounts
for kidneys anatomy and gives information on the
spatial distribution of the R2* map in the cortex and
medulla without using arbitrarily defined and
operator-dependent regions of interest.
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