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Abstract #0468

Evaluation of Multi-Modality Renal Functional MRI in Healthy Volunteers and Lupus Nephritis Patients

Stanislas Rapacchi 1,2 , Robert X Smith 3 , Yi Wang 3 , Lirong Yan 3 , Victor Sigalov 4 , Elizabeth Hernandez 5 , Ajay Verma 6 , Nicolas Wisniacki 7 , Jaime Torrington 6 , Xiang He 8 , Peng Hu 4 , George Karpouzas 5 , Ping-Chun Chiao 6 , and Danny JJ Wang 3

1 CRMBM, Aix-Marseille University, Marseille, France, 2 Radiology, UCLA, Los Angeles, CA, United States, 3 Neurology, UCLA, California, United States, 4 Radiology, UCLA, California, United States, 5 Rheumatology, Harbor-UCLA Medical Center, California, United States, 6 Biogen Idec, Cambridge, MA, United States, 7 Biogen Idec, MA, United States, 8 University of Pittsburg, PA, United States

This study evaluates the test-retest repeatability and the sensitivity of a multi-modality renal functional MRI protocol including diffusion weighted imaging (DWI), blood oxygen level dependent (BOLD), T1rho MRI and arterial spin labeling (ASL) in a cohort of healthy subjects (NC) and lupus nephritis (LN) patients.

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