Validation of Variable Flip Angle Imaging-Based Simultaneous B1+ and T1 Mapping in the Prostate at 3T

Characterizing B1+ distributions accurately is essential in multiparametric quantitative MRI; however, B1+ measurement sequences are additional to quantitative protocols and increase scan duration. This study aimed to characterize the B1+ distribution in the pelvis using a recently proposed reference region variable flip angle (RR-VFA) imaging based technique and compare it with a conventionally available B1+ mapping sequence in the prostate of healthy volunteers. The proposed technique showed B1+ distributions consistent with the conventional B1+ measurement technique, eliminating the need for an additional scan for B1+ correction. Additionally T1 measurements after B1+ correction with the RR-VFA method had significantly lower standard deviations, indicating improved robustness after B1+ correction.

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