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Abstract #0493

Direct calculation of B1 + and B1 - from two point variable flip angle data for quantitative T1 and PD mapping

Simon Baudrexel 1,2 , Ulrike Noeth 2 , Sarah Reitz 1,2 , Johannes Christian Klein 1,2 , and Ralf Deichmann 2

1 Department of Neurology, Goethe University Frankfurt, Frankfurt am Main, Germany, 2 Brain Imaging Center (BIC), Goethe University Frankfurt, Frankfurt am Main, Germany

A technique for direct calculation of the transmitted radio frequency (RF) field (B1 + ) and the receiver sensitivity profile (B1 - ) is presented which is based on the acquisition of a standard spoiled gradient echo sequence using two different flip angles (i.e. the variable flip angle method, VFA) without requiring any further measurements. In a sample of 12 healthy subjects, B1 + and B1 - maps obtained with the new method were compared with respective maps based on existing techniques, yielding very good agreement throughout the brain with an average absolute deviation of 3%.

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