Meeting Banner
Abstract #0518

Intracranial atherosclerotic lesion characteristics correlate with cerebrovascular lesion load after TIA or ischemic stroke: a 7.0 tesla MRI study

Nikki Dieleman 1 , Anja G. van der Kolk 1 , Jaco J.M. Zwanenburg 1,2 , Manon Brundel 3 , Anita A. Harteveld 1 , Geert Jan Biessels 3 , Fredy Visser 1,4 , Peter R. Luijten 1 , and Jeroen Hendrikse 1

1 Radiology, University Medical Center Utrecht, Utrecht, Utrecht, Netherlands, 2 Image Science Institute, University Medical Center Utrecht, Utrecht, Netherlands, 3 Neurology, University Medical Center Utrecht, Utrecht, Netherlands, 4 Philips, Best, Netherlands

In this prospective study we investigated the presence of cortical microinfarcts (CMIs) at 7.0 tesla MRI in patients with a transient ischemic attack or ischemic stroke of the anterior circulation and explored the relationship between intracranial atherosclerosis (ICAS), CMIs and macroinfarcts. This study shows that in CMIs represent a relevant portion of the total cerebrovascular lesion load and coexist with macroinfarcts. Furthermore, specific ICAS characteristics correlate with a higher cerebrovascular lesion load suggesting that ICAS may be a shared etiology. These results shine new light on the spectrum of parenchymal damage caused by ICAS.

This abstract and the presentation materials are available to members only; a login is required.

Join Here