Characterization of rat spinal cord vasoreactivity using arterial spins labelling at 9.4 T
Mohamed Tachrount 1 , Andrew Davies 2 , Roshni Desai 2 , Kenneth Smith 2 , David Thomas 1 , and Xavier Golay 1
UCL Institute of Neurology, London, London,
of Neuroinflammation, UCL Institute of Neurology,
London, United Kingdom
For the first time, the feasibility of measuring
vasoreactive changes in SCBF to a carbogen challenge in
healthy rats was shown. Different areas of the spinal
cord show different reactivity with a high degree of
reproducibility. These preliminary results highlight the
potential of the developed technique in the
investigation of the pathogenesis of neuroinflammatory
diseases such as Multiple Sclerosis.
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