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Abstract #0537

Quantitative rat lumbar spinal cord blood flow measurements using multi-slice arterial spin labelling at 9.4T

Mohamed Tachrount 1 , Andrew Davies 2 , Roshni Desai 2 , Kenneth Smith 2 , David Thomas 3 , Xavier Golay 1 , and Roshni Desai 2

1 Department of brain repair and rehabilitation, UCL Institute of Neurology, London, London, United Kingdom, 2 Department of Neuroinflammation, UCL Institute of Neurology, London, United Kingdom, 3 UCL Institute of Neurology, London, United Kingdom

A new multi-slice ASL technique is detailed and applied to the study of rat spinal cord at 9.4T. The quantification of the spinal cord blood flow was performed using a pre-saturation FAIR Q2TIPS ASL technique based on the use of adiabatic RF pulses with a reduced FOV. The averaged perfusion within the GM (95.14.6ml/100g/min) was higher than within the WM (39.73.2ml/100g/min).

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