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Abstract #0538

Measuring myocardial blood flow using modified look locker inversion (MOLLI) recovery arterial spin labelling (ASL)

Charlotte E Buchanan 1 , Eleanor F Cox 1 , Claire Grant 2 , Nick M Selby 2 , Chris W McIntyre 3 , Maarten W Taal 2 , and Susan T Francis 1

1 SPMIC, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom, 2 Division of Medical Sciences and Graduate Entry Medicine, Royal Derby Hospital, Nottingham, United Kingdom, 3 Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada

A modified look locker inversion (MOLLI) recovery arterial spin labelling (ASL) technique is used to measure myocardial blood flow (MBF) in humans. Cardiac triggering was used with a Trigger-delay (TD) prior to the label module to allow data to be collected at a range of post-label delay times. 8 TD values were collected (0 - 350 ms), with 3 readout pulses per Look-Locker set. MBF was 1.25 0.45 and 1.34 0.42 ml/g/min in healthy controls and chronic kidney disease patients. On exercise, the mean increase in MBF was 85 24 % for patients.

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