T2 texture change to articular cartilage over 6 months is associated with change to knee health and cartilage thickness over 2 years following ACL injury and reconstruction
Ashley A Williams 1 , Carl S Winalski 2 , and Constance R Chu 1
Orthopaedic Surgery, Stanford University,
Stanford, CA, United States,
Institute and Department Biomedical Engineering, Lerner
Research Institute, Cleveland Clinic, Cleveland, OH,
Patients who suffer ACL tear and reconstruction are at
heightened risk of developing osteaoarthritis.
Indications of future degeneration, including matrix
alterations characteristic of osteoarthritis, may be
present in cartilage shortly after ligament
reconstruction. Quantitative assessments of T2 maps of
19 ACL-injured subjects over 2 years indicate that
changes to T2 texture, but not T2 mean, observed over
the first 6 months following ACL reconstruction are
associated with 2-year change to cartilage thickness and
morphologic joint status. Textural and mean T2
differences between ACL-reconstructed and control
subjects observed at the time of ligament reconstruction
resolved over the following 2 years.
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