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Abstract #0578

T2 texture change to articular cartilage over 6 months is associated with change to knee health and cartilage thickness over 2 years following ACL injury and reconstruction

Ashley A Williams 1 , Carl S Winalski 2 , and Constance R Chu 1

1 Orthopaedic Surgery, Stanford University, Stanford, CA, United States, 2 Imaging Institute and Department Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States

Patients who suffer ACL tear and reconstruction are at heightened risk of developing osteaoarthritis. Indications of future degeneration, including matrix alterations characteristic of osteoarthritis, may be present in cartilage shortly after ligament reconstruction. Quantitative assessments of T2 maps of 19 ACL-injured subjects over 2 years indicate that changes to T2 texture, but not T2 mean, observed over the first 6 months following ACL reconstruction are associated with 2-year change to cartilage thickness and morphologic joint status. Textural and mean T2 differences between ACL-reconstructed and control subjects observed at the time of ligament reconstruction resolved over the following 2 years.

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