Meeting Banner
Abstract #0604

Quantitative DCE-MRI Evaluation of Breast Cancer Response to Neoadjuvant Chemotherapy

Alina Tudorica 1 , Karen Y Oh 1 , Stephen Y-C Chui 1 , Nicole Roy 1 , Megan L Troxell 1 , Arpana Naik 1 , Kathleen A Kemmer 1 , Yiyi Chen 1 , Megan L Holtorf 1 , Aneela Afzal 1 , Charles S Springer 1 , Xin Li 1 , and Wei Huang 1

1 Oregon Health & Science University, Portland, OR, United States

21 women with locally advanced breast cancer underwent DCE-MRI scans before, after the first cycle of, at the midpoint of, and after completion of neoadjuvant chemotherapy. Quantitative DCE-MRI parameters of Ktrans, kep, and Tau_i were found to be superior to tumor size measurement for early prediction of pathologic response. DCE-MRI parameters were as good as tumor size, if not better, in evaluation of residual disease burden after the therapy.

This abstract and the presentation materials are available to members only; a login is required.

Join Here