Abstract #0604
Quantitative DCE-MRI Evaluation of Breast Cancer Response to Neoadjuvant Chemotherapy
Alina Tudorica 1 , Karen Y Oh 1 , Stephen Y-C Chui 1 , Nicole Roy 1 , Megan L Troxell 1 , Arpana Naik 1 , Kathleen A Kemmer 1 , Yiyi Chen 1 , Megan L Holtorf 1 , Aneela Afzal 1 , Charles S Springer 1 , Xin Li 1 , and Wei Huang 1
1
Oregon Health & Science University,
Portland, OR, United States
21 women with locally advanced breast cancer underwent
DCE-MRI scans before, after the first cycle of, at the
midpoint of, and after completion of neoadjuvant
chemotherapy. Quantitative DCE-MRI parameters of Ktrans,
kep, and Tau_i were found to be superior to tumor size
measurement for early prediction of pathologic response.
DCE-MRI parameters were as good as tumor size, if not
better, in evaluation of residual disease burden after
the therapy.
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