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Abstract #0621

Improved Cardiac 1H-MR Spectroscopy at 3 T using High Permittivity Materials

Paul de Heer 1 , Maurice B Bizino 2 , Maarten J Versluis 1 , Andrew G Webb 1 , and Hildo J Lamb 2

1 CJ Gorter Center for High Field MRI, Radiology, Leiden University Medical Center, Leiden, Zuid Holland, Netherlands, 2 Radiology, Leiden University Medical Center, Leiden, Zuid Holland, Netherlands

Quantification of myocardial triglyceride content using cardiac proton magnetic resonance spectroscopy (1H-MRS) has proven to be important in the field of cardiovascular disease related to obesity, metabolic syndrome and diabetes mellitus type 2. However, cardiac 1H-MRS is challenging due to an intrinsic low signal-to-noise ratio (SNR). In this study we have shown in twenty healthy volunteers that by the application of the high permittivity pads the SNR increased from (meanSD) 27.915.6 to 42.324.4 (p<0.0001), resulting in a mean gain factor of 1.60.51 allowing a reduction in acquisition time by a factor of 2.5, without compromising spectral quality.

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