Abstract #0621
Improved Cardiac 1H-MR Spectroscopy at 3 T using High Permittivity Materials
Paul de Heer 1 , Maurice B Bizino 2 , Maarten J Versluis 1 , Andrew G Webb 1 , and Hildo J Lamb 2
1
CJ Gorter Center for High Field MRI,
Radiology, Leiden University Medical Center, Leiden,
Zuid Holland, Netherlands,
2
Radiology,
Leiden University Medical Center, Leiden, Zuid Holland,
Netherlands
Quantification of myocardial triglyceride content using
cardiac proton magnetic resonance spectroscopy (1H-MRS)
has proven to be important in the field of
cardiovascular disease related to obesity, metabolic
syndrome and diabetes mellitus type 2. However, cardiac
1H-MRS is challenging due to an intrinsic low
signal-to-noise ratio (SNR). In this study we have shown
in twenty healthy volunteers that by the application of
the high permittivity pads the SNR increased from
(meanSD) 27.915.6 to 42.324.4 (p<0.0001), resulting
in a mean gain factor of 1.60.51 allowing a reduction
in acquisition time by a factor of 2.5, without
compromising spectral quality.
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