Abstract #0640
            Comparison of optimized endovaginal vs. external array coil T2-W and Diffusion-Weighted imaging techniques for detecting suspected early stage (Ia/Ib1) uterine cervical cancer
                      Kate Downey                     1                    , Veronica Morgan                     1                    , 						Alison MacDonald                     1                    , Sharon Giles                     1                    , 						John Shepherd                     2                    , Thomas Ind                     2                    , Ayoma 						Attygalle                     3                    , Steve Hazell                     3                    , and 						Nandita deSouza                     1          
            
            1
           
           CRUK Cancer Imaging Centre, The Institute of 
						Cancer Research and The Royal Marsden Hospital, Sutton, 
						Surrey, United Kingdom,
           
            2
           
           Gynaecological 
						Surgery, The Royal Marsden Hospital, London, United 
						Kingdom,
           
            3
           
           Histopathology, 
						The Royal Marsden Hospital, London, United Kingdom
          
            
          Endovaginal MRI using T2-W sequences is more sensitive 
						(87% vs. 73.9%) but less specific (80% vs. 93.3%) than 
						equivalent optimized external array imaging for 
						detecting suspected Ia1/2 and Ib1 cervical tumors. 
						Addition of diffusion-weighted sequences to T2-W 
						protocols obtained with an endovaginal coil 
						substantially improves specificity (80% to 93.3%). 
						Addition of diffusion-weighted imaging to T2-W protocols 
						acquired using an external array coil however merely 
						serves to reduce sensitivity (73.9% to 65.2%) for 
						detecting these small (1cm) tumors.
         
				
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