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Abstract #0640

Comparison of optimized endovaginal vs. external array coil T2-W and Diffusion-Weighted imaging techniques for detecting suspected early stage (Ia/Ib1) uterine cervical cancer

Kate Downey 1 , Veronica Morgan 1 , Alison MacDonald 1 , Sharon Giles 1 , John Shepherd 2 , Thomas Ind 2 , Ayoma Attygalle 3 , Steve Hazell 3 , and Nandita deSouza 1

1 CRUK Cancer Imaging Centre, The Institute of Cancer Research and The Royal Marsden Hospital, Sutton, Surrey, United Kingdom, 2 Gynaecological Surgery, The Royal Marsden Hospital, London, United Kingdom, 3 Histopathology, The Royal Marsden Hospital, London, United Kingdom

Endovaginal MRI using T2-W sequences is more sensitive (87% vs. 73.9%) but less specific (80% vs. 93.3%) than equivalent optimized external array imaging for detecting suspected Ia1/2 and Ib1 cervical tumors. Addition of diffusion-weighted sequences to T2-W protocols obtained with an endovaginal coil substantially improves specificity (80% to 93.3%). Addition of diffusion-weighted imaging to T2-W protocols acquired using an external array coil however merely serves to reduce sensitivity (73.9% to 65.2%) for detecting these small (1cm) tumors.

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