Abstract #0644
Full 3D mapping of T2* relaxation times from mid to late gestation of the normal fetal brain
Anna I Blazejewska 1 , Sharmishtaa Seshamani 2 , Susan K McKown 3 , Jason S Caucutt 3 , Manjiri Dighe 3 , Christopher Gatenby 3 , and Colin Studholme 2
1
BICG, University of Washington, Seattle, WA,
United States,
2
BICG,
University of Washington, WA, United States,
3
University
of Washington, WA, United States
In this work, we examine an approach using one or more
dual echo multi-slice acquisitions that are themselves
then repeated and combined. Between-slice motion is then
estimated and the multiple echoes combined, allowing 3D
mapping of T2* values in the presence of fetal head
motion. We applied the methods to a cohort of healthy
fetuses from mid-gestation onwards. This importantly
provides a full 3D image and extends previously
published measurements below 26W into the 20-26W period
where many clinical MRIs are acquired after an earlier
ultra-sound evaluation of pregnancy.
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