Abstract #0646
Developmental characterization of sub-cortical white matter tracts
Adeoye Oyefiade 1 , Stephanie Ameis 2,3 , Nadia Scantlebury 1,2 , Alexandra Decker 2 , Kamila U Szulc 2 , and Donald J Mabbott 1,2
1
Psychology, The Hospital for Sick Children,
Toronto, ON, Canada,
2
Neurosciences
and Mental Health, The Hospital for Sick Children,
Toronto, ON, Canada,
3
Child and Youth Mental
Health, Center for Addiction and Mental Health, Toronto,
Toronto, ON, Canada
Neural communication is facilitated by white matter (WM)
comprised of both short and long-range tracts. Diffusion
tensor imaging (DTI) has successfully described the
developmental characteristics of long-range WM tracts.
There remains a limited understanding of these
characteristics in short-range tracts. Here, we used DTI
and probabilistic tractography to reconstruct
short-range white matter in a group of typically
developing children and adolescents. DT-MR images were
obtained for typically developing children and
adolescents. Results indicate significant age-related
changes in u-fibers across the brain with the exception
of the occipital lobes. Future studies will investigate
the relationship between these changes and cognitive
function.
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