Abstract #0649
Densely packed white matter regions are less prone to develop white matter hyperintensities
Robert S Vorburger 1 , Atul Narkhede 1 , Yunglin Gazes 1 , Vanessa A Guzman 1 , Yaakov Stern 1,2 , and Adam M Brickman 1,2
1
Taub Institute, Columbia University, New
York, New York, United States,
2
Department
of Neurology, Columbia University, New York, New York,
United States
FLAIR and DTI have been widely used to investigate
cerebral white matter changes of the aging brain. The
relationship between parameters derived from the two
techniques, such as white matter hyperintensities (WMH)
and fractional anisotropy (FA), is still poorly
understood. To investigate this relationship, a
reference FA map from a sample of young subjects and a
WMH probability map from a sample of elderly subjects
was computed. Regions with a high FA value in the young
brain show a significant lower WMH probability in the
elderly brain, indicating that densely packed fiber
tracts are less prone to develop WMH.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
