Abstract #0674
Simultaneous 18 F-FACBC PET/MRI for loco-regional staging of prostate cancer: considerations on imaging protocol design
Mattijs Elschot 1 , Kirsten M. Selns 1,2 , Brage Krger-Stokke 1,3 , ystein Strkersen 4 , Helena Bertilsson 5,6 , Siver A. Moestue 1,2 , and Tone F. Bathen 1,2
1
Department of Circulation and Medical
Imaging, Norwegian University of Science and Technology,
Trondheim, Sr-Trndelag, Norway,
2
St
Olavs Hospital, Trondheim, Sr-Trndelag, Norway,
3
Department
of Radiology, St Olavs Hospital, Trondheim,
Sr-Trndelag, Norway,
4
Department
of Pathology, St Olavs Hospital, Trondheim,
Sr-Trndelag, Norway,
5
Department
of Urology, St Olavs Hospital, Trondheim, Sr-Trndelag,
Norway,
6
Department
of Cancer Research and Molecular Medicine, Norwegian
University of Science and Technology, Trondheim,
Sr-Trndelag, Norway
18
F-FACBC PET/CT imaging has shown promise
for the assessment of primary and metastatic prostate
cancer, especially in conjoint use with MRI.
Simultaneous PET/MRI may therefore be an interesting
option, but designing the imaging protocol is
complicated by the fast kinetics of
18
F-FACBC
and the long scan time required for multiparametric MRI.
Based on the dynamic uptake of
18
F-FACBC
in 11 patients that underwent PET/MRI for pre-operative
staging of high-risk prostate cancer, we propose a
realistic protocol that includes 45 minutes of PET
imaging in addition to all MRI sequences required for
clinical evaluation of the prostate and pelvic lymph
nodes.
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