Abstract #0675
Multiparametric hybrid 18FDG-PET/MRI in patients with Multiple Myeloma: initial experience
Jennifer Mosebach 1 , Christos Sachpekidis 2 , Martin Freitag 1 , Jens Hillengass 3 , Antonia Dimitrakopoulou-Strauss 2 , Uwe Haberkorn 4 , Heinz-Peter Schlemmer 1 , and Stefan Delorme 1
1
Department of Radiology, German Cancer
Research Center, Heidelberg, Germany,
2
Clinical
Cooperation Unit Nuclear Medicine, German Cancer
Research Center, Heidelberg, Germany,
3
Department
of Medicine V, Multiple Myeloma Section, University of
Heidelberg, Heidelberg, Germany,
4
Division
of Nuclear Medicine, University of Heidelberg,
Heidelberg, Germany
Hybrid PET/MRI examinations offer an innovative approach
to simultaneously depict metabolic as well as functional
and anatomical MR parameters. Fifteen patients newly
diagnosed with Multiple Myeloma received whole body
PET/MRI including Diffusion-weighted Imaging (DWI).
Lesion by lesion based analysis as well as comparison of
standard-uptake-values (SUV) and
Apparent-diffusion-coefficient (ADC)- values were
conducted. For the detection of focal bone marrow
infiltrates, PET and DWI can be complementary, with PET
displaying more lesions located in ribs, whereas DWI
seems to have advantages discovering lesions masked by
the surrounding diffuse myeloma infiltrate. Those
patients could therefore especially benefit from
multimodality imaging.
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