Abstract #0676
4D ECHO PLANAR CORRELATED SPECTROSCOPIC IMAGING AND DWI OF BREAST CANCER
Rajakumar Nagarajan 1 , Neil Wilson 1 , Nanette DeBruhl 1 , Brian Burns 1 , Melissa Joines 1 , Maithili Gopalakrishnan 1 , Fausto Rendon 1 , Lawrence W Bassett 1 , and M.Albert Thomas 1
1
Radiological Sciences, UCLA School of
Medicine, Los Angeles, CA, United States
Early detection and diagnosis are essential for
successful treatment of breast cancer. Magnetic
Resonance Spectroscopy (MRS) can provide high
specificity for distinguishing benign from malignant
lesions. The four dimensional (4D) echo-planar
correlated spectroscopic imaging (EP-COSI) enables full
slice coverage of the breast facilitating recording of
multi-voxel based two-dimensional (2D) MRS than the
single-voxel based localized correlated spectroscopy
(L-COSY). The 4D EP-COSI offers improved spectral
dispersion and sensitivity compared with 1D MRS data.
Decreased ADC values derived from diffusion weighted
imaging (DWI) can be correlated with increased choline
and decreased lipids quantified by the EP-COSI
technique.
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