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Abstract #0677

Relaxation-weighted sodium MRI of breast lesions at 7T

Stefan Zbyn 1 , Olgica Zaric 1 , Vladimir Juras 1 , Katja Pinker 2 , Alex Farr 3 , Nadia Benkhedah 4 , Pascal Balzer 2 , Vladimir Mlynarik 1 , Armin Nagel 4 , Christian Singer 3 , Thomas Helbich 2 , Wolfgang Bogner 1 , and Siegfried Trattnig 1

1 High Field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2 Division of Molecular and Gender Imaging, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 3 Department of Gynecology and Obstetrics, Medical University of Vienna, Vienna, Austria, 4 Department of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

The aim of this study was to compare total sodium signal with relaxation-weighted sodium signal in breast lesions at 7T. While conventional sodium density images showed a signal proportional to the local sodium concentration, sodium ions with a longer T2*, such as in a cyst or edema, were well suppressed in relaxation-weighted images. Our data demonstrated improved differentiation between edema, benign lesion and breast cancer with relaxation-weighted sodium images than with conventional sodium density images. Combined information from conventional and from relaxation-weighted sodium images may improve noninvasive evaluation of breast lesions.

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