Meeting Banner
Abstract #0686

Evaluating the Feasibility of Monitoring In Vivo Spinal Cord Metabolism Using Hyperpolarized Carbon-13 MR Spectroscopic Imaging

Ilwoo Park 1 , Jason F. Talbott 1,2 , and Sarah J. Nelson 1,3

1 Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, 2 Brain and Spine Injury Center (BASIC), San Francisco General Hospital, San Francisco, CA, United States, 3 Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, CA, United States

This study has demonstrated the feasibility of using hyperpolarized 13 C MR imaging with [1- 13 C]pyruvate for evaluating in vivo metabolism of spinal cord. High pyruvate and relatively small lactate signal were observed in the cervical spinal cord of uninjured rats. The results from this study suggest that this technique may provide a unique non-invasive imaging tool that is able to monitor biochemical processes underlying spinal cord injury.

This abstract and the presentation materials are available to members only; a login is required.

Join Here