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Abstract #0690

High resolution magnetic resonance elastography of the human eye in vivo: a feasibility study

Jrgen Braun 1 , Sebastian Hirsch 2 , Jing Guo 2 , Katharina Erb-Eigner 2 , and Ingolf Sack 2

1 Department of Medical Informatics, Charit - Universittsmedizin Berlin, Berlin, Berlin, Germany, 2 Department of Radiology, Charit - Universittsmedizin Berlin, Berlin, Germany

The feasibility of in vivo MR-elastography (MRE) of human eyes is demonstrated. A clinically applicable actuator for inducing shear waves into the eye was constructed which could be combined with a standard head coil and a specialized eye coil. 3D MRE of 90 and 100 Hz vibration frequency and 1mm^3 cubic voxel resolution was used for reconstructing viscoelastic parameter maps of magnitude and phase angle of the complex shear modulus. We measured a magnitude modulus of 1084 plus-or-minus sign 366 Pa in the vitreous body which agrees to in-vivo values obtained in the mouse.

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