High resolution magnetic resonance elastography of the human eye in vivo: a feasibility study
Jrgen Braun 1 , Sebastian Hirsch 2 , Jing Guo 2 , Katharina Erb-Eigner 2 , and Ingolf Sack 2
Department of Medical Informatics, Charit -
Universittsmedizin Berlin, Berlin, Berlin, Germany,
of Radiology, Charit - Universittsmedizin Berlin,
The feasibility of in vivo MR-elastography (MRE) of
human eyes is demonstrated. A clinically applicable
actuator for inducing shear waves into the eye was
constructed which could be combined with a standard head
coil and a specialized eye coil. 3D MRE of 90 and 100 Hz
vibration frequency and 1mm^3 cubic voxel resolution was
used for reconstructing viscoelastic parameter maps of
magnitude and phase angle of the complex shear modulus.
We measured a magnitude modulus of 1084
Pa in the vitreous body which agrees to in-vivo values
obtained in the mouse.
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