Effect of the Number of Echoes and Reconstruction model on the Precision and Reproducibility of T 2 Measurments in Myocardial T 2 Mapping

Quantitative myocardial T ₂ mapping allows non-invasive assessment of myocardial inflammation/edema. Recent implementations use T ₂ -prepared (T ₂ prep) SSFP sequences to acquire multiple T ₂ weighted images at different echo times, then generate the T ₂ maps based on a 2-parameter fitting (2P-fit) model of T ₂ decay. Recently, a 3-parameter fitting (3P-fit) model was found superior to the conventional 2P-fit model, as it compensates for T1 relaxation effect, and results in more accurate T ₂ measurements. In this work, we sought to characterize the 3P-fit approach in terms of precision and reproducibility and to evaluate the influence of the number of employed T ₂ prep echo times on these two metrics.

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