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Abstract #0719

Endogenous assessment of chronic myocardial infarction with T1 -mapping in patients

Joep van Oorschot 1 , Hamza El Aidi 1 , Fredy Visser 2 , Pieter Doevendans 1 , Peter Luijten 1 , Tim Leiner 1 , and Jaco Zwanenburg 1

1 University Medical Center Utrecht, Utrecht, Utrecht, Netherlands, 2 Philips Healthcare, Best, Noord-Brabant, Netherlands

Studies in animal models have shown that cardiac T1ρ-mapping can be used to detect myocardial fibrosis without the use of a contrast agent. In this study we performed cardiac T1ρ-mapping for detection of chronic MI in 21 patients, and compared it with the LGE method. A significantly higher T1ρ relaxation time was found in the infarct region (79 11 ms), compared to healthy remote myocardium (55 6 ms). A sensitivity of 0.77 and a specificity of 0.73 was found for T1ρ-mapping compared to LGE imaging.

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