Stretched-exponential model DWI (SEM-DWI) as a potential imaging biomarker in grading gliomas and assessment of proliferative activity

Diffusion wighted imaging (DWI) is one of the advanced neuroimaging techniques in the evaluation of brain tumors. Stretched exponential model DWI (SEM-DWI) is one of them which can properly describe the signal intensity decay when b-factor exceeds 1000 s/mm2. Proliferating cell nuclear antigen (PCNA) and Ki-67 are two of the common nuclear markers in proliferation activity evaluation. In this study, we will assess the feasibility of SEM-DWI in grading gliomas and to find the correlation between DWI parameters and PCNA and Ki-67 labeling index (LI) thus to evaluate DWI as a noninvasive technique for evaluating the proliferative characteristics of gliomas.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.