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Abstract #0749

Skeletal muscle oxygen extraction fraction measurement - at rest and during ischemia

Chengyan Wang 1 , Rui Zhang 2 , Xiaodong Zhang 3 , He Wang 4 , Kai Zhao 3 , Jue Zhang 1,2 , Xiaoying Wang 1,3 , and Jing Fang 1,2

1 Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, Beijing, China, 2 College of Enigneering, Peking University, Beijing, China, 3 Department of Radiology, Peking University First Hospital, Beijing, China, 4 Philips Research China, Shanghai, Shanghai, China

The tissue oxygen extraction fraction (OEF) is an important physiological quantity, particularly in organs such as skeletal muscle, in which oxygen delivery and use are tightly coupled. The purpose of this study was to develop a reliable method to directly quantify regional skeletal muscle OEF at rest and during ischemia. The tissue oxygen extraction fraction (OEF) is an important physiological quantity, particularly in organs such as skeletal muscle, in which oxygen delivery and use are tightly coupled. The purpose of this study was to develop a reliable method to directly quantify regional skeletal muscle OEF at rest and during ischemia.

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