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Abstract #0757

T1rho and T2 relaxation times in patients with knee osteoarthritis at 3 Tesla and 7 Tesla

Cory Wyatt 1 , Aditi Guha 1 , Anand Venkatachari 1 , Xiaojuan Li 1 , Roland Krug 1 , Douglas A.C. Kelley 2 , Thomas M. Link 1 , and Sharmila Majumdar 1

1 Radiology, University of California San Francisco, San Francisco, California, United States, 2 GE Healthcare Technologies, San Francisco, California, United States

Twenty patients, seven without knee osteoarthritis and thirteen with osteoarthritis, were scanned at 3T and 7T with T1rho and T2 mapping sequences. The mean T1rho and T2 in six cartilage compartments in the knee were compared between the healthy controls and the patients with osteoarthritis. Results showed more significant differences between groups in the 7T relaxation values compared to the 3T values, suggesting the possibility of the use of smaller cohort sizes at 3T to detect changes in cartilage composition.

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