Abstract #0760
Ultra-short T E STEAM improves hepatic lipid quantification and profiling at 7T
Martin Gajdok 1 , Grzegorz Chadzynski 2,3 , Vladimr Mlynrik 1 , Marek Chmelk 1 , Wolfgang Bogner 1 , Ladislav Valkovic 1,4 , Ivica Just Kukurov 1 , Siegfried Trattnig 1 , and Martin Krk 1,5
1
MRCE, Department of Biomedical Imaging and
Image-guided Therapy, Medical University of Vienna,
Vienna, Austria,
2
Department
of Biomedical Magnetic Resonance, University of
Tbingen, Tbingen, Germany,
3
Department
of High-Field Magnetic Resonance, Max Planck Institute
for Biological Cybernetics, Tbingen, Germany,
4
Institute
of Measurement Science, Slovak Academy of Sciences,
Bratislava, Slovakia,
5
Department
of Internal Medicine III, Medical University of Vienna,
Vienna, Austria
Previous
1
H
MRS measurements in the brain have demonstrated
advantages of ultra-short T
E
at
ultra-high fields. Besides higher SNR, T
2
relaxation
and J-modulation effects in the spectra can be
minimized. This is of particular importance in the liver
tissue, where both effects along with iron deposition
have to be taken into account. The STEAM with T
E
=6ms
provided higher SNR and reproducibility for precise
estimation of HCL. Furthermore the high spectral
resolution at 7T with sufficient CRLBs of single lipid
resonances highlights the potential of this sequence to
be used in advanced studies of hepatic lipid profiles
in
vivo
.
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