High resolution spectroscopic imaging with ultra short TE in patients with multiple sclerosis and brain tumors at 7T
Gilbert Hangel 1 , Bernhard Strasser 1 , Michal Povaan 1 , Stephan Gruber 1 , Marek Chmelik 1 , Georg Widhalm 2 , Engelbert Knosp 2 , Assunta Dal-Bianco 3 , Fritz Leutmezer 3 , Siegfried Trattnig 1 , and Wolfgang Bogner 1
MCRE, Department of Biomedical Imaging and
Image-guided Therapy, Medical University of Vienna,
Wien, Vienna, Austria,
of Neurosurgery, Medical University of Vienna, Wien,
of Neurology, Medical University of Vienna, Wien,
This work presents the application of single- and
multi-slice accelerated high resolution FID-based
spectroscopic imaging sequences with ultra-short TE in
patients with multiple sclerosis and brain tumors at 7T.
Using the parallel imaging method CAIPIRINHA for 2D and
3D acceleration, the measurement time for a single slice
6464 matrix could be reduced to 6:00 minutes, as well
as 22:35 minutes for a 64644 matrix, allowing the
inclusion into a standard imaging protocol. The acquired
metabolic maps correlated well with lesions found on
anatomical images, indicating a possible future use in
diagnostics for multiple sclerosis and brain tumors.
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