Abstract #0765
Giant Intracranial Aneurysms at 7 Tesla MRI: A New Diagnostic Approach to Understand This Rare Intracranial Vascular Pathology
Bixia Chen 1,2 , Toshinori Matsushige 2,3 , Stefan Maderwald 1 , Sren Johst 1 , Harald H. Quick 1,4 , Mark Edward Ladd 1,5 , Ulrich Sure 2 , and Karsten Henning Wrede 1,2
1
Erwin L. Hahn Institute for Magnetic
Resonance Imaging, University Duisburg-Essen, Essen,
NRW, Germany,
2
Department
of Neurosurgery, University Hospital Essen, University
Duisburg-Essen, Essen, NRW, Germany,
3
Department
of Neurosurgery, Hiroshima University Hospital,
Hiroshima University, Hiroshima, Hiroshima Prefecture,
Japan,
4
High
Field and Hybrid MR Imaging, University Hospital Essen,
University Duisburg-Essen, Essen, NRW, Germany,
5
Medical
Physics in Radiology, German Cancer Research Center
(DKFZ), Heidelberg, BW, Germany
Intracranial giant aneurysms (IGA) were prospectively
analyzed at 7T MRI, focusing on the aneurysm wall. Six
patients were examined in a 7T whole-body MR scanner
with a 32-channel head coil. TOF, MPRAGE, and SWI
sequences were acquired. Two surgically resected
aneurysms were suitable for histological examination. 7T
TOF and SWI could precisely reveal microstructures and
iron deposition in individual layers of the aneurysm
wall as seen in histopathology. Measurement of wall
thickness on 7T TOF corresponded best with
histopathological findings. Ultra-high-field MRI of this
rare intracranial vascular pathology can contribute to
understanding the complex pathophysiology of aneurysm
growth and rupture.
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