An investigation of Lateral Geniculate Nucleus (LGN) volume in patients with glaucoma using 7T MRI.
Hye Jin Jeong 1 , Jong Yeon Lee 2 , Jong Hwan Lee 2 , Yu Jeong Kim 2 , Eung Yeop Kim 3 , Yong Yeon Kim 4 , Zang-Hee Cho 1 , and Young-Bo Kim 1
Neuroscience Research Institute, Gachon
University, Incheon, Korea,
of Ophthalmology, Gachon University, Gil Hospital,
Department of Radiology,
Gachon University, Incheon, Korea,
of Ophthalmology, Korea University College of Medicine,
To investigate lateral geniculate nucleus (LGN) volume
of glaucoma patients compared with age-matched normal
controls using ultra-high field 7.0-T magnetic resonance
imaging (MRI). On high-resolution 7.0-T MRI, LGN volumes
in POAG patients are significantly smaller than those of
healthy subjects. Furthermore, in patients, LGN volume
was found to be significantly correlated with ganglion
cell layer and inner plexus layer (GCIPL) thickness of
the contralateral eye.
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