Abstract #0763
In-vivo proton MR spectroscopic imaging of the human brain gliomas at 9.4 Tesla: evaluation of metabolite coordinates
Grzegorz L. Chadzynski 1,2 , Gisela Hagberg 1,2 , Jonas Bause 2 , G. Shajan 2 , Sotirios Bisdas 3 , Rolf Pohmann 2 , and Klaus Scheffler 1,2
1
Dept. Biomedical Magnetic Resonance,
University of Tuebingen, Tuebingen, Germany,
2
Dept.
High-field Magnetic Resonance, Max Planck Institute for
Biological Cybernetics, Tuebingen, Germany,
3
Dept.
Diagnostic and Interventional Neuroradiology, University
of Tuebingen, Tuebingen, Germany
Recently it was demonstrated that the advantages of
ultra-high field MR spectroscopic imaging (MRSI), namely
the better signal-to-noise ratio and the improved
spectral resolution, can be useful in clinical
applications. Studies conducted at lower field strengths
(below 3T) have shown that an evaluation with the
Orthonormal Discriminant Vector method (ODV) enables
differentiation between low (WHO grade II and III) and
high grade (WHO grade IV) human brain tumors. The aim of
this study was to verify the usefulness of the ODV
method in assessing human brain tumor spectra measured
with MRSI at a field strength of 9.4T.
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