Abstract #0762
In vivo MR Microscopy of the Nervus Opticus at 3.0 T and 7.0 T: Anatomical and Diffusion Weighted Imaging in Healthy Subjects and Patients with Optic Nerve Glioma
Katharina Paul 1 , Andreas Graessl 1 , Jan Rieger 1 , Darius Lysiak 1 , Till Huelnhagen 1 , Lukas Winter 1 , Antje Els 1 , Beate Endemann 1 , Tobias Lindner 2 , Stefan Hadlich 3 , Paul-Christian Krueger 3 , Oliver Stachs 2,4 , Soenke Langner 3 , and Thoralf Niendorf 1,5
1
Max-Delbrueck Centre for Molecular Medicine,
Berlin Ultrahigh Field Facility (B.U.F.F.), Berlin,
Berlin, Germany,
2
University
Medicine Rostock, Pre-clinical Imaging Research Group,
Rostock, Germany,
3
University
of Greifswald, Institute for Diagnotic Radiology and
Neuroradiology, Greifswald, Germany,
4
University
Medicine Rostock, Department of Ophthalmology, Rostock,
Germany,
5
Experimental
and Clinical Research Center, a joint cooperation
between the Charite Medical Faculty and the
Max-Delbrueck Center, Berlin, Germany
This work demonstrates the feasibility of in vivo MR
microscopy of the optic nerve at 3.0 T and 7.0 T
including T
1
-weighted, T
2
-weighted
anatomical imaging along with ADC mapping. Imaging the
optic nerve and other extra-ocular structures benefits
from the spatial resolution enhancements at (ultra)high
fields. The detail, integrity and image quality
demonstrated for T
1
weighted
3D FLASH imaging, T
2
weighted
RARE imaging and for ADC mapping underscore the value of
dedicated RF coil hardware in conjunction with the
signal gain at ultrahigh fields for advancing the
capabilities of anatomical imaging and DWI of the eye,
orbit and optic nerve.
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