Meeting Banner
Abstract #0762

In vivo MR Microscopy of the Nervus Opticus at 3.0 T and 7.0 T: Anatomical and Diffusion Weighted Imaging in Healthy Subjects and Patients with Optic Nerve Glioma

Katharina Paul 1 , Andreas Graessl 1 , Jan Rieger 1 , Darius Lysiak 1 , Till Huelnhagen 1 , Lukas Winter 1 , Antje Els 1 , Beate Endemann 1 , Tobias Lindner 2 , Stefan Hadlich 3 , Paul-Christian Krueger 3 , Oliver Stachs 2,4 , Soenke Langner 3 , and Thoralf Niendorf 1,5

1 Max-Delbrueck Centre for Molecular Medicine, Berlin Ultrahigh Field Facility (B.U.F.F.), Berlin, Berlin, Germany, 2 University Medicine Rostock, Pre-clinical Imaging Research Group, Rostock, Germany, 3 University of Greifswald, Institute for Diagnotic Radiology and Neuroradiology, Greifswald, Germany, 4 University Medicine Rostock, Department of Ophthalmology, Rostock, Germany, 5 Experimental and Clinical Research Center, a joint cooperation between the Charite Medical Faculty and the Max-Delbrueck Center, Berlin, Germany

This work demonstrates the feasibility of in vivo MR microscopy of the optic nerve at 3.0 T and 7.0 T including T 1 -weighted, T 2 -weighted anatomical imaging along with ADC mapping. Imaging the optic nerve and other extra-ocular structures benefits from the spatial resolution enhancements at (ultra)high fields. The detail, integrity and image quality demonstrated for T 1 weighted 3D FLASH imaging, T 2 weighted RARE imaging and for ADC mapping underscore the value of dedicated RF coil hardware in conjunction with the signal gain at ultrahigh fields for advancing the capabilities of anatomical imaging and DWI of the eye, orbit and optic nerve.

This abstract and the presentation materials are available to members only; a login is required.

Join Here