Abstract #0769
The evaluation of the white matter development and small-world networks in the fetal brain MRI using sBTFE sequence
Bing Zhang # 1 , Chenchen Yan # 1 , Ming Li 1 , Huiting Wang 1 , Zuzana Nedelska 2 , Tong Ru 3 , Zhiqun Wang 3 , Jie Li 3 , Jian Yang 4 , Yali Hu* 3 , and Bin Zhu* 1
1
Department of Radiology, The Affiliated Drum
Tower Hospital of Nanjing University Medical School,
Nanjing, China,
2
Memory
Disorders Clinic,Department of Neurology, Charles
University, 2nd Faculty of Medicine and Motol University
Hospital, Czech Republic,
3
Department
of Gynaecology and Obstetrics, The Affiliated Drum Tower
Hospital of Nanjing University Medical School, Nanjing,
China,
4
Department
of Radiology, The First Affiliated Hospital of Medical
College, Xi'an Jiaotong University, Xi'an, China
We aimed to examine the white matter development and
small-world networks in 150 fetal brains across the
different gestational weeks using sBTFE on MRI. The
bilateral prefrontal signal intensity during gestational
week 21-23 was lower than other subplate zones,
consistent with the germinal matrix being present that
region at that time. The lower degree of the connection
pattern in brain at gestational week 25 could be due to
the unsynchronized cellular migration within brain
regions. And the similar pattern of the small-world
properties between gestational weeks 28 and 33-39
indicated the fetal brain was maturating after
gestational week 28.
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