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Abstract #0803

Adipokine secretions correlate with MRI measurements of adiposity

Kathryn Murray 1 , Caroline Hoad 1 , Jill Garratt 2 , Carolyn Costigan 1 , Arvind Batra 3 , Britta Siegmund 3 , Yirga Falcone 2 , Jan Smith 2 , Eleanor Cox 1 , Jan Paul 1 , David Humes 2 , Susan Francis 1 , Luca Marciani 2 , Robin Spiller 2 , and Penny Gowland 1

1 Sir Peter Mansfield Imaging Centre, Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom, 2 Nottingham Digestive Diseases Biomedical Research Centre, Nottingham University Hospitals, Nottingham, United Kingdom, 3 Gastroenterology, Rheumatology, Infectious Diseases, Charit Universittsmedizin, Berlin, Germany

This study highlights the relationship between adipose deposition, adipokine secretion and intestinal inflammation using obese and non-obese patients with diverticular disease. DIXON imaging was used to determine VAT, SAT and TAT amounts and these volumes were compared to concentrations of adiponectin, leptin and calprotectin. These novel insights will help improve our understanding of the relationship between visceral fat, obesity and inflammation.

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