Abstract #0829
Diffusion kurtosis imaging quantifies the effects of mild traumatic brain injury in football players
Daniel Olson 1 , Melissa Lancaster 2 , Ashley LaRoche 3 , Volkan Arpinar 3 , Michael McCrea 3 , and L Tugan Muftuler 3
1
Biophysics, Medical College of Wisconsin,
Milwaukee, Wisconsin, United States,
2
Neurology,
Medical College of Wisconsin, Wisconsin, United States,
3
Neurosurgery,
Medical College of Wisconsin, Wisconsin, United States
Mild traumatic brain injury (mTBI) is a prevalent injury
for athletes in contact sports. In order to study
changes in brain tissue microstructure after mTBI, we
used Diffusion Kurtosis Imaging (DKI), an extension of
DTI. DKI complements DTI by estimating non-Gaussianity
of the molecular diffusion in complex tissue
microstructures; therefore, it is hypothesized to be
more sensitive and specific to subtle microstructural
changes due to mild concussion. Radial kurtosis was
significantly reduced in athletes with concussions.
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