Meeting Banner
Abstract #0829

Diffusion kurtosis imaging quantifies the effects of mild traumatic brain injury in football players

Daniel Olson 1 , Melissa Lancaster 2 , Ashley LaRoche 3 , Volkan Arpinar 3 , Michael McCrea 3 , and L Tugan Muftuler 3

1 Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States, 2 Neurology, Medical College of Wisconsin, Wisconsin, United States, 3 Neurosurgery, Medical College of Wisconsin, Wisconsin, United States

Mild traumatic brain injury (mTBI) is a prevalent injury for athletes in contact sports. In order to study changes in brain tissue microstructure after mTBI, we used Diffusion Kurtosis Imaging (DKI), an extension of DTI. DKI complements DTI by estimating non-Gaussianity of the molecular diffusion in complex tissue microstructures; therefore, it is hypothesized to be more sensitive and specific to subtle microstructural changes due to mild concussion. Radial kurtosis was significantly reduced in athletes with concussions.

This abstract and the presentation materials are available to members only; a login is required.

Join Here