Abstract #0830
Altered Cortical and Subcortical Functional Connectivity in a Single Football Season
Bryson B. Reynolds 1 , Todd M. Chatlos 1 , Donna K. Broshek 2 , Max Wintermark 3 , Susan F. Saliba 4 , Howard P. Goodkin 5 , and T. Jason Druzgal 1
1
Radiology and Medical Imaging, University of
Virginia School of Medicine, Charlottesville, Virginia,
United States,
2
Psychiatry
and Neurobehavioral Sciences, University of Virginia
School of Medicine, Charlottesville, Virginia, United
States,
3
Radiology,
Stanford School of Medicine, San Francisco, CA, United
States,
4
Kinesiology,
University of Virginia Curry School, Charlottesville,
VA, United States,
5
Neurology,
University of Virginia Health System, Charlottesville,
VA, United States
Biomechanical head impact data shows that football
players receive significantly more severe and more
numerous subconcussive impacts than lacrosse players.
Our data shows that in football players (N=21) there are
significant increases in cortical-cortical functional
connectivity and significant decreases in subcortical-cortical
functional connectivity during the span of a season as
measured by rs-fMRI (p<0.001), however there were no
observed changes in lacrosse players during a practice
season (N=30). Our preliminary data presents a
compelling argument that rs-fMRI is capable of detecting
and demonstrating physiologic changes in a single
football season, likely caused by subconcussive impacts.
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