Abstract #0838
Does using a 16-element receive-array improve whole-liver 31 P metabolite ratio quantification at 7T?
Lucian A. B. Purvis 1 , William T. Clarke 1 , Michael Pavlides 1 , Stefan Neubauer 1 , Matthew D. Robson 1 , and Christopher T. Rodgers 1
1
Department of Cardiovascular Medicine,
University of Oxford, Oxford, Oxfordshire, United
Kingdom
Using a 16-element receive array at 7T permitted precise
quantification of
31
P
metabolite ratios from the whole liver, in a study on 5
normal volunteers. A 3D UTE-CSI sequence gave an average
of 27 voxels (each 6.3mL nominal volume) of high quality
data for each subject. The inter-subject mean and SD of
the metabolite ratios (averaged over all voxels) were
then calculated: 36.4 6.94 for PME/PDE, 44.4 3.93
for GPC/Total Ester and 12.6 3.58 for PE/Total Ester.
This preliminary work will inform the design of future
clinical studies of diseases such as non-alcoholic fatty
liver disease.
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