Abstract #0883
Stimulated Echo Diffusion Tensor Imaging with Varying Diffusion Times as a Probe of Breast Tissue
Jose R. Teruel 1,2 , Gene Y. Cho 3,4 , Jason Ostenson 4 , Melanie Moccaldi 5 , Joon Lee 5 , Pl E. Goa 2,6 , Tone F. Bathen 1 , Sungheon G. Kim 3,4 , Linda Moy 4,5 , and Eric E. Sigmund 3,4
1
Circulation and Medical Imaging, Norwegian
University of Science and Technology, Trondheim, Norway,
2
St.Olavs
Hospital, Trondheim, Norway,
3
Center
for Advanced Imaging Innovation and Research (CAI2R),
New York University School of Medicine, New York, NY,
United States,
4
Bernard
and Irene Schwartz Center for Biomedical Imaging,
Department of Radiology, New York University School of
Medicine, New York, NY, United States,
5
Cancer
Institute, New York University Langone Medical Center,
New York, NY, United States,
6
Department
of Physics, Norwegian University of Science and
Technology, Trondheim, Norway
The purpose of this study is to characterize the length
scales of breast tissue using a stimulated echo
acquisition mode (STEAM) diffusion tensor imaging (DTI)
sequence with variable diffusion times. The evolution of
the radial diffusivity with diffusion time was used to
calculate the surface-to-volume ratio applying the Mitra
early time limit model. This analysis may provide an in
vivo non-invasive tool to probe diffusion lengths in
healthy and pathological breast tissue.
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