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Abstract #0892

Imaging oxygen extraction fraction in the visual cortex during functional activation using turbo QUIXOTIC

Jeffrey N Stout 1 , Elfar Adalsteinsson 1,2 , Bruce R Rosen 3 , and Divya S Bolar 3,4

1 Harvard-MIT Health Sciences and Technology, Institute of Medical Engineering and Science, Cambridge, Massachusetts, United States, 2 Department of Electrical Engineering and Computer Science, MIT, MA, United States, 3 Martinos Center for Biomedical Imaging, MGH/Harvard Medical School, MA, United States, 4 Department of Radiology, Massachusetts General Hospital, Boston, MA, United States

Using a turbo spin echo version of QUIXOTIC we measure changes in oxygen extraction fraction (OEF) in the visual cortex at baseline and during visual stimulation in a fraction of the time required by the original QUIXOTIC technique. The measured baseline and relative change in oxygen extraction fraction (OEF) compares favorably to literature values and suggests that with further validation tQUIXOTIC MRI may be useful to monitor regional OEF in the clinic.

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