Abstract #0904
Impact of intra- and juxta-cortical pathology on cognitive impairment in multiple sclerosis by quantitative T 2 * mapping at 7 T MRI
Cline Louapre 1 , Sindhuja T Govindarajan 1 , Costanza Giann 1 , Nancy Madigan 2 , AS Nielsen 3 , RP Kinkel 4 , and Caterina Mainero 1
1
AA. Martinos Center for Biomedical Imaging,
Charlestown, MA, United States,
2
Beth
Israel Deaconess Medical Center, Boston, MA, United
States,
3
Virginia
Mason Medical Center, Seattle, WA, United States,
4
University
of California San Diego, San Diego, CA, United States
This study aims at determining the relation between
nueropsychological performance in patients with multiple
sclerosis and cortical tissue damage at different depths
through the cortical width up to the juxta-cortical
white matter, across the whole brain. Therefore, we use
a quantitative, surface-based analysis of T
2
*
relaxation rates from ultra high resolution 7 Tesla MRI.
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