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Abstract #0928

Vector Model for Quantitative Susceptibility Mapping (Vector QSM)

Tian Liu 1,2 , Cynthia Wisnieff 2,3 , Dong Zhou 2 , Pascal Spincemaille 2 , and Yi Wang 2,3

1 MedImageMetric LLC, New York, NY, United States, 2 Radiology, Weill Cornell Medical College, New York, NY, United States, 3 Biomedical Engineering, Cornell University, Ithaca, NY, United States

A vector model for quantitative susceptibility mapping (vector QSM) is proposed, allowing the reconstruction of a susceptibility vector map from a single orientation. Compared to scalar QSM, the vector QSM models the magnetic field inhomogeneity better and improves image quality with reduced signal variation. Compared to susceptibility tensor imaging (STI), vector QSM drastically reduces the required number of scans and has improved signal to noise ratio. Vector QSM may be useful in studying multiple sclerosis lesions to investigate the molecular underpinning of longitudinal susceptibility changes.

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