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Abstract #0929

Human cortical surface maps of three quantitative imaging parameters:R_1, R_2^* and Magnetic Susceptibility

Diana Khabipova 1 , Rolf Gruetter 1,2 , and Jos P. Marques 1

1 CIBM, Lausanne, Vaud, Switzerland, 2 Radiology, University of Lausanne and Geneva, Vaud, Switzerland

This study compares the ability of the different contrasts (R1, R2star and Susceptibility) to provide insights into the cortical brain structure. The cortical R1 and R*2 maps shown show similar contrast to that reported by other groups. The χ, as opposed to R1 maps and R*2, does not decrease monotonically from inner surfaces to outer surfaces, suggests that myelin and iron contributions are cancelling each other and might have distinguishable cortical distributions. Combination of information using different contrasts at different depths could provide useful information for cortical segmentation as is supported by the reproducibility of the single subject data.

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