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Abstract #0976

Bicuspid Valve Morphology Determines the Position of Elevated Velocity and WSS: 4D Flow MRI in 202 Subjects

Pim van Ooij 1,2 , Ian G Murphy 2 , Alexander L Powell 2 , Maria Carr 2 , Wouter V Potters 1 , Colleen Clennon 3 , Jeremy D Collins 2 , James C Carr 2 , S Chris Malaisrie 4 , Patrick M McCarthy 3 , Michael Markl 2,5 , and Alex J Barker 2

1 Radiology, Academic Medical Center, Amsterdam, Netherlands, 2 Radiology, Northwestern University, Chicago, IL, United States, 3 Division of Cardiac Surgery, Northwestern University, Chicago, IL, United States, 4 Medicine-Cardiology, Northwestern University, Chicago, IL, United States, 5 Northwestern University, Biomedical Engineering, Chicago, IL, United States

Bicuspid valve (BAV) patients are known to express two different types of aortic dilation: 1) with involvement of the root or 2) dilation of the distal aorta. In this 4D flow MRI study, 140 BAV patients are compared with 60 volunteers. With advanced postprocessing techniques (cohort-averaged and P-value maps) it is shown that differences in BAV opening lead to differences in velocity and WSS expression that may be related to the different types of dilation.

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