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Abstract #0984

Removal of Nuisance Signals from Limited and Sparse 3D 1 H-MRSI Data of the Brain

Bryan Clifford 1 , Chao Ma 2 , Fan Lam 1 , and Zhi-Pei Liang 1

1 Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 2 Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, United States

We present a post-processing method for the removal of water and lipid signals from 3D 1 H-MRSI data that has limited and sparse coverage of (k, t) -space. Our method extends a recently proposed Union-of-Subspace method to enable the use of support constraints derived from high-resolution 3D anatomical scans. The method is capable of handling 3D data sets with only a limited number of spatial encodes in the slice direction. Experimental results show that the proposed method can effectively remove water and lipid signals from 3D 1 H-MRSI data of the brain. The method is particularly useful for accelerated 1 H-MRSI with sparse sampling.

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