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Abstract #0983

Mechanisms of SNR Enhancement and Line Shape Improvement in B 0 Correction for Overdiscrete MRSI Reconstruction

Thomas Kirchner 1 , Ariane Fillmer 1 , Klaas Paul Pruessmann 1 , and Anke Henning 1,2

1 Institute for Biomedical Engineering, UZH and ETH Zurich, Zurich, Switzerland, 2 Max Planck Institute for Biological Cybernetics, Tuebingen, Germany

Spatial variations in the main magnetic field are a common source of artifacts in brain MRSI. When using overdiscrete target-driven reconstruction of 1 H FID MRSI at 7T, improvements not only in spectral SNR but also in metabolite line width are achieved by performing B 0 correction at a subvoxel level. The mechanisms behind these effects are spatial noise decorrelation and frequency alignment. Additional optimization of the FID acquisition time in conjunction with zero-filling is shown to be largely complementary and allows to further increase SNR enhancement.

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