Abstract #0990
3D MR spectroscopic imaging using adiabatic spin echo and hypergeometric dual band pulses for metabolic mapping over the entire brain
Morteza Esmaeili 1,2 , Tone Frost Bathen 2 , Bruce R. Rosen 1 , and Ovidiu Cristian Andronesi 1
1
Athinoula A. Martinos Center for Biomedical
Imaging, Department of Radiology, Massachusetts General
Hospital, Harvard Medical School, Boston, MA, United
States,
2
Department
of Circulation and Medical Imaging, Norwegian University
of Science and Technology (NTNU), Trondheim, Norway
Full head proton magnetic resonance spectroscopic
imaging (MRSI) is desirable to map metabolites over the
entire brain but challenging due to large artifacts
created by lipid signals. Hypergeometric dual band
pulses have a very sharp passband and when combined with
adiabatic spin echo and MEGA editing provide efficient
lipid and water suppression for full brain metabolic
imaging. Here we show that such a combined approach is
robust with respect to B1 inhomogeneity at 3T and is
superior to traditional suppression schemes for 3D MRSI
of full brain.
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