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Abstract #0995

Further Evidence of an Orientation Dependence of Magnetization Transfer Parameters from Investigations in Post-Mortem Marmoset Brain

Henrik Marschner 1 , Riccardo Metere 1 , Stefan Geyer 1 , Andr Pampel 1 , and Harald E. Mller 1

1 Nuclear Magnetic Resonance, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Sachsen, Germany

We examine the apparent dependence of qMT parameters, in particular those of the T2b relaxation time of bound protons, on the white matter fiber orientation in a Post-Mortem Marmoset Brain. The observed angular dependence in the post-mortem data for highly ordered WM supports the hypothesis of orientation dependence of the RF absorption lineshape that was observed in human brain in vivo. Here, variation of the orientation is achieved by rotating the sample in the magnetic field.

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