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Abstract #1031

Imposing label priors in global tractography can resolve crossing fibre ambiguities

Daan Christiaens 1,2 , Frederik Maes 1,2 , Stefan Sunaert 2,3 , and Paul Suetens 1,2

1 Electrical Engineering, KU Leuven, Leuven, Vlaams-Brabant, Belgium, 2 Medical Imaging Research Center, UZ Leuven, Leuven, Vlaams-Brabant, Belgium, 3 Translational MRI, KU Leuven, Leuven, Vlaams-Brabant, Belgium

Ambiguity in the local diffusion profile is an important cause of spurious fibre tracks in DWI. We propose to use bundle labels as an additional prior in global tractography to overcome this issue. We have evaluated such label prior in a Tractometer study, and demonstrated its effect on real data using the Catani atlases of 30 white matter tracts. Results show an important decrease of invalid connections and spurious tracks. Additionally, a probabilistic segmentation of the fibre bundles is obtained.

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