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Abstract #1032

Connectivity based segmentation of the Corpus Callosum using a novel data mining approach

Gowtham Atluri 1 , An Wu 2 , Essa Yacoub 2 , Kamil Ugurbil 2 , Vipin Kumar 1 , and Christophe Lenglet 2

1 Computer Science and Engineering, University of Minnesota, Minneapolis, Minnesota, United States, 2 Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, United States

Existing approaches that are used to do finer segmentation of cortical regions using DTI based tractography data do not make use of the underlying spatial structure. In this work, we extend a popular Shared Nearest Neighbor (SNN) based clustering approach in order to account for spatial structure in the data. We use this approach to discover finer segmentation of the Corpus Callosum in 2 normal subjects using tractography data computed from a 3T and a 7T DTI scan. Our results suggest that our new approach results in a segmentation that is consistent between 3T and 7T.

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