Correlation of 3D MR-Based Percent Breast Density with Apparent Diffusion Coefficient of the Breast Fibroglandular Tissue
Jeon-Hor Chen 1,2 , Hon J Yu 1 , Yifan Li 1 , Yoon Jung Choi 3 , Po Yun Huang 4 , and Min-Ying Su 1
Center for Functional Onco-Imaging,
University of California, Irvine, CA, United States,
of Radiology, Eda Hospital and I-Shou University,
of Radiology, Kangbuk Samsung Hospital, Seoul, Korea,
of Medical Imaging, China Medical University, Taichung,
This study investigated the association of 3D MR-based
breast density with apparent diffusion coefficient (ADC)
acquired from the fibroglandular tissue of the breast.
MR images from the contralateral normal breast of 38
women diagnosed with unilateral breast cancer were
retrospectively analyzed. The results from our study
noted a positive correlation of ADC values with
MR-measured percent breast density. This study proved
that women with higher breast density had higher stromal
matrix, which can be assessed using ADC.
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